| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM82_2206 | coaD | DM82_2206 | DM82_3731 | Hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.730 |
| DM82_2206 | gmk | DM82_2206 | DM82_2205 | Hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.959 |
| cmk | coaD | DM82_2141 | DM82_3731 | Cmk: cytidylate kinase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.595 |
| cmk | gmk | DM82_2141 | DM82_2205 | Cmk: cytidylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.741 |
| cmk | guaA | DM82_2141 | DM82_1711 | Cmk: cytidylate kinase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.461 |
| cmk | ribF | DM82_2141 | DM82_298 | Cmk: cytidylate kinase. | ribF: riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.777 |
| cmk | rsmD | DM82_2141 | DM82_3730 | Cmk: cytidylate kinase. | RNA methyltransferase, RsmD family. | 0.603 |
| coaBC | coaD | DM82_295 | DM82_3731 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.949 |
| coaBC | coaE | DM82_295 | DM82_2677 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.832 |
| coaBC | coaX | DM82_295 | DM82_3610 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase, type III family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.937 |
| coaBC | gmk | DM82_295 | DM82_2205 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.571 |
| coaBC | guaA | DM82_295 | DM82_1711 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.571 |
| coaBC | ribF | DM82_295 | DM82_298 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | ribF: riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.845 |
| coaD | DM82_2206 | DM82_3731 | DM82_2206 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Hypothetical protein. | 0.730 |
| coaD | cmk | DM82_3731 | DM82_2141 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Cmk: cytidylate kinase. | 0.595 |
| coaD | coaBC | DM82_3731 | DM82_295 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.949 |
| coaD | coaE | DM82_3731 | DM82_2677 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.945 |
| coaD | coaX | DM82_3731 | DM82_3610 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantothenate kinase, type III family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.959 |
| coaD | fdx_2 | DM82_3731 | DM82_3732 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 4Fe-4S dicluster domain protein. | 0.697 |
| coaD | gmk | DM82_3731 | DM82_2205 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.651 |