Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhBTransketolase, C-terminal domain protein. (326 aa)    
Predicted Functional Partners:
lpdA-2
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.999
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
bkdA1
2-oxoisovalerate dehydrogenase subunit alpha.
 0.999
acoA
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.
 0.998
pdhC
E3 binding domain protein.
 
 0.998
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 0.995
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.991
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.984
pflB
Pyr_form_ly_1: formate acetyltransferase.
   
 
 0.938
sucB
Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.926
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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