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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)    
Predicted Functional Partners:
lpdA-2
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.999
pdhB
Transketolase, C-terminal domain protein.
 0.999
acoB
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta.
 0.998
pdhC
E3 binding domain protein.
 
 0.998
bkdA2
2-oxoisovalerate dehydrogenase subunit beta.
 0.998
aceF
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.989
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.985
acoC
Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system.
 
 0.982
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.977
maeB_1
Malic enzyme, NAD binding domain protein.
  
 
 0.957
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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