Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)    
Predicted Functional Partners:
pdhB
Transketolase, C-terminal domain protein.
 0.999
bkdA2
2-oxoisovalerate dehydrogenase subunit beta.
 0.999
acoB
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta.
 0.998
pdhC
E3 binding domain protein.
 
 0.998
lpdA-2
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.997
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 0.991
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.978
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 
 0.965
pflB
Pyr_form_ly_1: formate acetyltransferase.
   
 
 0.931
aceF
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.929
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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