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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyk-3Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family. (484 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.990
pgi
Phosphoglucose isomerase family protein; Belongs to the GPI family.
 
 
 0.980
maeB_1
Malic enzyme, NAD binding domain protein.
  
 0.960
maeB
NADP-dependent malic enzyme; Belongs to the malic enzymes family.
  
 0.960
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.936
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.930
pgk
Phosphoglycerate kinase family protein; Belongs to the phosphoglycerate kinase family.
 
 
 0.927
ldhA
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
  
 0.924
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 
0.922
spoT
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.922
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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