Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyk-3Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family. (484 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.988
pgi
Phosphoglucose isomerase family protein; Belongs to the GPI family.
 
 0.974
maeB_1
Malic enzyme, NAD binding domain protein.
  
 0.953
maeB
NADP-dependent malic enzyme; Belongs to the malic enzymes family.
  
 0.953
tkt
Transketolase; Tktlase_bact: transketolase; Belongs to the transketolase family.
  
 0.932
pgk
Phosphoglycerate kinase family protein; Belongs to the phosphoglycerate kinase family.
 
 
 0.925
ldhA
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
  
 0.923
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 
0.922
pflB
Pyr_form_ly_1: formate acetyltransferase.
   
 
 0.921
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.920
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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