STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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cobAcobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (254 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
cobI
Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
 
 0.951
hemX
uroporphyrinogen-III synthase HemD family protein.
 
 
 0.951
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.929
cobA-2
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase.
  
  
 
0.914
cysH
Adenylylsulfate reductase, thioredoxin dependent family protein; Reduction of activated sulfate into sulfite.
 
  
 0.891
hemB
Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family.
 
  
 0.888
sir_2
Nitrite and sulphite reductase 4Fe-4S domain protein.
 
  
 0.867
cysD_2
Phosphoadenosine phosphosulfate reductase family protein.
 
  
 0.863
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
  
 0.848
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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