Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbiXCobalamin (Vitamin B12) biosynthesis CbiX protein. (128 aa)    
Predicted Functional Partners:
cobI
Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
    
 0.932
lptF
Putative permease YjgP/YjgQ family protein.
  
    0.829
lptG
Putative permease YjgP/YjgQ family protein.
  
    0.824
cobJ
cobJ_cbiH: precorrin-3B C17-methyltransferase.
 
   
 0.711
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.698
pepA
Hypothetical protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
       0.657
cobA-2
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase.
  
  
 0.645
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit.
     
 0.630
cysD_1
Phosphoadenosine phosphosulfate reductase family protein.
 
  
 0.585
cysD_2
Phosphoadenosine phosphosulfate reductase family protein.
 
  
 0.585
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (12%) [HD]