| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpA | grpE | DM82_290 | DM82_2499 | clpA: ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.799 |
| clpA | hslV | DM82_290 | DM82_3390 | clpA: ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.417 |
| clpA | hspA_2 | DM82_290 | DM82_4038 | clpA: ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. | 0.620 |
| clpA | htpG | DM82_290 | DM82_513 | clpA: ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity. | 0.602 |
| clpB | grpE | DM82_1528 | DM82_2499 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.784 |
| clpB | hslV | DM82_1528 | DM82_3390 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.417 |
| clpB | hspA_2 | DM82_1528 | DM82_4038 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. | 0.638 |
| clpB | htpG | DM82_1528 | DM82_513 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity. | 0.602 |
| clpV | grpE | DM82_2780 | DM82_2499 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.779 |
| clpV | hslV | DM82_2780 | DM82_3390 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.417 |
| clpV | hspA_2 | DM82_2780 | DM82_4038 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. | 0.612 |
| clpV | htpG | DM82_2780 | DM82_513 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity. | 0.602 |
| clpV-2 | grpE | DM82_4624 | DM82_2499 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.779 |
| clpV-2 | hslV | DM82_4624 | DM82_3390 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.417 |
| clpV-2 | hspA_2 | DM82_4624 | DM82_4038 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. | 0.634 |
| clpV-2 | htpG | DM82_4624 | DM82_513 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity. | 0.602 |
| clpV-3 | grpE | DM82_4982 | DM82_2499 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | grpE family protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.779 |
| clpV-3 | hslV | DM82_4982 | DM82_3390 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.417 |
| clpV-3 | hspA_2 | DM82_4982 | DM82_4038 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Hsp20/alpha crystallin family protein; Belongs to the small heat shock protein (HSP20) family. | 0.611 |
| clpV-3 | htpG | DM82_4982 | DM82_513 | VI_ClpV1: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity. | 0.602 |