close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thcD_2Pyridine nucleotide-disulfide oxidoreductase family protein. (757 aa)    
Predicted Functional Partners:
andAb_2
Rieske [2Fe-2S] domain protein.
 
 0.826
andAb_1
Rieske [2Fe-2S] domain protein.
  
 0.802
nirD
nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit.
 
 0.799
nirD-2
nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit.
 
 0.759
DM82_2069
Rieske [2Fe-2S] domain protein.
  
 0.722
rubA
Rubredoxin family protein.
  
 
 0.708
DM82_493
Rubredoxin family protein.
  
 
 0.708
DM82_5653
Hypothetical protein.
  
 
 0.708
thcB
Cytochrome domain protein; P450 116; Belongs to the cytochrome P450 family.
 
  
 0.703
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.599
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.