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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvC_2Acetohydroxy acid isomeroreductase, catalytic domain protein; Belongs to the ketol-acid reductoisomerase family. (353 aa)    
Predicted Functional Partners:
ilvN
Acolac_sm: acetolactate synthase, small subunit.
 
 
 0.997
ilvD
ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.996
ilvB
Acolac_lg: acetolactate synthase, large subunit, biosynthetic type.
 
 
 0.988
ilvB_2
Thiamine pyrophosphate enzyme, central domain protein.
 
 
 0.987
ilvG
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family.
 
 
 0.982
ilvB_1
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family.
 
 
 0.982
budB
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family.
 
 
 0.975
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.967
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.965
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
  
 0.964
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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