STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
puuC_1Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (479 aa)    
Predicted Functional Partners:
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.927
bclA_2
AMP-binding enzyme family protein.
   
 0.927
bclA_1
AMP-binding enzyme family protein.
   
 0.927
gabT-2
GABAtrnsam: 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.920
mmsA-2
MMSDH: methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.919
mmsA
MMSDH: methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.918
mmsA-3
MMSDH: methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.917
flhA_2
adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.915
gabD_1
Aldehyde dehydrogenase family protein.
  
  
 
0.915
fadJ_1
enoyl-CoA hydratase/isomerase family protein.
  
 0.914
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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