| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM82_1437 | acs | DM82_1437 | DM82_4474 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
| DM82_1437 | bclA_1 | DM82_1437 | DM82_820 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | AMP-binding enzyme family protein. | 0.927 |
| DM82_1437 | bclA_2 | DM82_1437 | DM82_4713 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | AMP-binding enzyme family protein. | 0.927 |
| DM82_1437 | gabT-2 | DM82_1437 | DM82_4283 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | GABAtrnsam: 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.920 |
| DM82_1437 | garR_3 | DM82_1437 | DM82_4068 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | Ketopantoate reductase PanE/ApbA family protein. | 0.907 |
| DM82_1437 | mmsA-2 | DM82_1437 | DM82_4714 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.918 |
| DM82_1437 | mmsB | DM82_1437 | DM82_4715 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | HIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.911 |
| DM82_1437 | prpC | DM82_1437 | DM82_4211 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family. | 0.848 |
| DM82_1437 | pta_2 | DM82_1437 | DM82_6247 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | Phosphate acetyl/butaryl transferase family protein. | 0.842 |
| DM82_1437 | puuC_1 | DM82_1437 | DM82_450 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.913 |
| acs | DM82_1437 | DM82_4474 | DM82_1437 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.927 |
| acs | bclA_1 | DM82_4474 | DM82_820 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-binding enzyme family protein. | 0.914 |
| acs | bclA_2 | DM82_4474 | DM82_4713 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-binding enzyme family protein. | 0.921 |
| acs | garR_3 | DM82_4474 | DM82_4068 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Ketopantoate reductase PanE/ApbA family protein. | 0.806 |
| acs | mmsA-2 | DM82_4474 | DM82_4714 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.927 |
| acs | mmsB | DM82_4474 | DM82_4715 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | HIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.830 |
| acs | prpC | DM82_4474 | DM82_4211 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family. | 0.952 |
| acs | pta_2 | DM82_4474 | DM82_6247 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphate acetyl/butaryl transferase family protein. | 0.952 |
| acs | puuC_1 | DM82_4474 | DM82_450 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.927 |
| bclA_1 | DM82_1437 | DM82_820 | DM82_1437 | AMP-binding enzyme family protein. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.927 |