STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hpaHhpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase. (267 aa)    
Predicted Functional Partners:
hpaI
hpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 0.999
hpaD
hpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.977
hpaG
hpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit.
 
 
 0.973
hpaG-2
hpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit.
 
 
 0.972
hpcD
5-carboxymethyl-2-hydroxymuconate isomerase family protein.
 
  
 0.965
bphJ
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.962
garL
5-keto-4-deoxy-D-glucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 0.950
hpcB_2
Catalytic LigB subunit of aromatic ring-opening dioxygenase family protein.
 
  
 0.935
hpaR
hpaR: homoprotocatechuate degradation operon regulator, HpaR.
 
   
 0.806
dmpG
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.796
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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