close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaIhpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (268 aa)    
Predicted Functional Partners:
hpaH
hpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
 
 0.999
hpcD
5-carboxymethyl-2-hydroxymuconate isomerase family protein.
 
  
 0.970
hpaD
hpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.924
gabD_3
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.904
gabD
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.904
hpaE
hpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.760
hpaR
hpaR: homoprotocatechuate degradation operon regulator, HpaR.
 
   
 0.724
hpcB_2
Catalytic LigB subunit of aromatic ring-opening dioxygenase family protein.
 
  
 0.703
mhpD_2
Fumarylacetoacetate (FAA) hydrolase family protein.
 
  
 0.682
hpaG
hpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit.
 
  
 0.599
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.