| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| copR_1 | cusS_1 | DM82_4822 | DM82_4821 | Response regulator. | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | 0.996 |
| copR_1 | czcA_2 | DM82_4822 | DM82_4825 | Response regulator. | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.654 |
| copR_1 | oprM_6 | DM82_4822 | DM82_4823 | Response regulator. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.698 |
| copR_1 | ttgA | DM82_4822 | DM82_4824 | Response regulator. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.689 |
| cusS_1 | copR_1 | DM82_4821 | DM82_4822 | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | Response regulator. | 0.996 |
| cusS_1 | czcA_2 | DM82_4821 | DM82_4825 | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.667 |
| cusS_1 | oprM_6 | DM82_4821 | DM82_4823 | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.682 |
| cusS_1 | ttgA | DM82_4821 | DM82_4824 | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.691 |
| czcA | ttgA | DM82_5191 | DM82_4824 | Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.682 |
| czcA_2 | copR_1 | DM82_4825 | DM82_4822 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Response regulator. | 0.654 |
| czcA_2 | cusS_1 | DM82_4825 | DM82_4821 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Heavy metal sensor kinase family protein; Member of a two-component regulatory system. | 0.667 |
| czcA_2 | oprM_6 | DM82_4825 | DM82_4823 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.844 |
| czcA_2 | ttgA | DM82_4825 | DM82_4824 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.971 |
| macB_1 | oprM_6 | DM82_4719 | DM82_4823 | ABC transporter family protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.949 |
| macB_1 | ttgA | DM82_4719 | DM82_4824 | ABC transporter family protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.988 |
| mdtC_1 | ttgA | DM82_1691 | DM82_4824 | MMPL family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.686 |
| mdtC_2 | oprM_6 | DM82_1825 | DM82_4823 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.432 |
| mdtC_2 | ttgA | DM82_1825 | DM82_4824 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.769 |
| mdtC_3 | mdtC_4 | DM82_684 | DM82_685 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | MMPL family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.799 |
| mdtC_3 | oprM_6 | DM82_684 | DM82_4823 | acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein. | 0.443 |