Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
czcA_2acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1068 aa)    
Predicted Functional Partners:
ttgA
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 0.996
mexA
Multidrug resistance protein mexA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.932
mdtC_1
MMPL family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 
0.924
oprM_3
Outer membrane efflux family protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
 0.922
tolC
Outer membrane efflux family protein.
  
 0.922
mdtE_1
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.916
acrB_2
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein.
  
  
 
0.906
mexA_1
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.881
oprM_6
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein.
 
 
 0.842
mdtE_2
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.755
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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