Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ophA1_12Fe-2S iron-sulfur cluster binding domain protein. (329 aa)    
Predicted Functional Partners:
yiiM
MOSC domain protein.
   
 0.884
kshA_1
Ring hydroxylating alpha subunit family protein.
 
   
 0.749
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.739
antA
Ring hydroxylating alpha subunit family protein.
 
  
 0.718
iscU
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.713
nifU_2
SUF_scaf_2: SUF system FeS assembly protein, NifU family.
  
 0.713
citT
Citrate transporter family protein.
     
 0.704
andAc
Ring hydroxylating alpha subunit family protein.
 
  
 0.677
ppsE_2
AMP-binding enzyme family protein.
   
 0.672
pksM
Thioester-redct: thioester reductase domain protein.
   
 0.668
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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