Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aphA_1Histone deacetylase domain protein. (341 aa)    
Predicted Functional Partners:
hflB-2
ftsH_fam: ATP-dependent metallopeptidase HflB family protein; Belongs to the AAA ATPase family.
 
 
 0.786
DM82_5294
WD domain, G-beta repeat family protein.
  
 
 0.775
DM82_2636
Hypothetical protein.
    
 0.714
DM82_3101
Double zinc ribbon family protein.
   
 
 0.645
DM82_837
Caspase domain protein.
   
 0.590
htpG
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; Molecular chaperone. Has ATPase activity.
    
 0.577
DM82_1577
Ankyrin repeat family protein.
   
 0.549
ndk
Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.547
DM82_2273
Sir2 family protein.
    
 0.515
cobB_2
Sir2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
    
 0.515
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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