Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcCCobalt-zinc-cadmium resistance protein CzcC. (452 aa)    
Predicted Functional Partners:
czcB
Cobalt-zinc-cadmium resistance protein CzcB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.976
czcA
Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.941
cusA
2A0601: heavy metal efflux pump, CzcA family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.723
cusS_2
Heavy metal sensor kinase family protein; Member of a two-component regulatory system.
 
     0.706
macB_1
ABC transporter family protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.667
cusB
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.661
copR_2
Response regulator.
 
   0.649
bepF
RND_mfp: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.571
czcB_2
RND_mfp: efflux transporter, RND family, MFP subunit.
 
 
 0.562
DM82_6220
hlyD secretion family protein.
 
 
 0.510
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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