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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mhpD_2Fumarylacetoacetate (FAA) hydrolase family protein. (256 aa)    
Predicted Functional Partners:
dmpG
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.955
bphJ
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.939
hpcD
5-carboxymethyl-2-hydroxymuconate isomerase family protein.
 
  
 0.891
hpaH
hpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
  
   
 0.695
hpaI
hpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.682
garL
5-keto-4-deoxy-D-glucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.660
hpaD
hpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.655
hpcB_2
Catalytic LigB subunit of aromatic ring-opening dioxygenase family protein.
 
  
 0.597
ygiD
Catalytic LigB subunit of aromatic ring-opening dioxygenase family protein.
  
  
 0.446
thcB
Cytochrome domain protein; P450 116; Belongs to the cytochrome P450 family.
 
   
 0.416
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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