Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (565 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
 
 0.992
betI
Transcriptional repressor BetI; Repressor involved in choline regulation of the bet genes.
 
  
 0.812
plcA_1
Phosphoesterase family protein.
     
  0.800
plcN_2
PC_PLC: phospholipase C, phosphocholine-specific.
     
  0.800
DM82_2150
Ribosomal RNA adenine dimethylase family protein.
     
  0.800
plcA_2
Phosphoesterase family protein.
     
  0.800
plcN_3
PC_PLC: phospholipase C, phosphocholine-specific.
     
  0.800
plcN_4
Phosphoesterase family protein.
     
  0.800
plcB_2
Phosphoesterase family protein.
     
  0.800
psd
Phosphatidylserine decarboxylase family protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
     
  0.800
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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