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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAPTS system fructose-specific EIIBC component. (646 aa)    
Predicted Functional Partners:
ptsP-2
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
 
 
 0.999
lacC
1-PFK: hexose kinase, 1-phosphofructokinase family protein; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
ptsP-3
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase.
 
 
 0.999
ptsH
PTS_HPr_: phosphocarrier, HPr family protein.
 
 
 0.991
pfkB
Putative phosphofructokinase pfkB; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.990
crh
PTS HPr component phosphorylation site family protein.
  
 
 0.989
ptsP
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.965
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component.
 
  
 0.952
fba
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.950
sacC
Hypothetical protein; Glycosyl hydrolases family 32 N-terminal domain protein; Belongs to the glycosyl hydrolase 32 family.
  
 
 0.948
Your Current Organism:
Burkholderia oklahomensis
NCBI taxonomy Id: 342113
Other names: B. oklahomensis, Burkholderia oklahomensis Glass et al. 2006, CCUG 51349, DSM 21774, LMG 23618, LMG:23618, NCTC 13387, strain C6786
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