STRINGSTRING
obg protein (Staphylococcus saprophyticus) - STRING interaction network
"obg" - GTPase Obg in Staphylococcus saprophyticus
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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obgGTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family (431 aa)    
Predicted Functional Partners:
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (334 aa)
   
        0.981
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20 (102 aa)
 
  0.976
rpmA
50S ribosomal protein L27; Similar to gi|57284712|gb|AAW36806.1| [Staphylococcus aureus subsp. aureus COL], percent identity 93 in 94 aa, BLASTP E()- 2e-44; Belongs to the bacterial ribosomal protein bL27 family (94 aa)
 
  0.917
SSP1116
UPF0735 ACT domain-containing protein SSP1116; Similar to gi|57284710|gb|AAW36804.1| [Staphylococcus aureus subsp. aureus COL], percent identity 74 in 151 aa, BLASTP E()- 1e-57; Belongs to the UPF0735 family (151 aa)
         
  0.896
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (607 aa)
   
   
  0.894
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (200 aa)
              0.865
der
GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis (436 aa)
 
   
  0.833
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (876 aa)
 
 
  0.817
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (145 aa)
 
 
  0.795
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5’-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (207 aa)
   
 
  0.792
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 342451
Other names: S. saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus, Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus ATCC15305, Staphylococcus saprophyticus subsp. saprophyticus CIP 76.125, Staphylococcus saprophyticus subsp. saprophyticus DSM 20229, Staphylococcus saprophyticus subsp. saprophyticus NCTC 7292, Staphylococcus saprophyticus subsp. saprophyticus str. ATCC 15305, Staphylococcus saprophyticus subsp. saprophyticus strain ATCC 15305
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