STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Patl_0338PFAM: cyclic-AMP phosphodiesterase, class-II; KEGG: vfi:VF1256 3',5'-cyclic-nucleotide phosphodiesterase. (339 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.916
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.912
Patl_0494
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase Tetratricopeptide TPR_2; KEGG: lic:LIC20094 adenylate/guanylate cyclase.
    
  0.905
Patl_2382
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: ana:all0661 adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
  0.905
Patl_0139
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: cps:CPS_0423 HAD-superfamily hydrolase, subfamily IA, variant 3 family protein.
     
  0.900
Patl_2381
KEGG: pha:PSHAa1692 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
  0.900
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
  0.900
Patl_3194
PFAM: conserved hypothetical protein 730; KEGG: cps:CPS_3537 lysine decarboxylase family protein.
     
  0.900
Your Current Organism:
Pseudoalteromonas atlantica
NCBI taxonomy Id: 342610
Other names: P. atlantica T6c, Pseudoalteromonas atlantica T6c, Pseudoalteromonas atlantica str. T6c, Pseudoalteromonas atlantica strain T6c
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