STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
Patl_1798
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: yps:YPTB1146 succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.995
Patl_1797
KEGG: pha:PSHAa1649 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.991
Patl_1800
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.990
Patl_1795
PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: pha:PSHAa1651 putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with SdhD.
  
 
 0.989
Patl_1799
KEGG: cps:CPS_2219 2-oxoglutarate dehydrogenase, E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component Transketolase, central region.
 
 0.980
Patl_1796
Succinate dehydrogenase subunit D; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.968
Patl_1114
PFAM: biotin/lipoyl attachment catalytic domain of components of various dehydrogenase complexes E3 binding; KEGG: bur:Bcep18194_A5442 dihydrolipoamide acetyltransferase.
  
 0.938
Patl_3351
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.938
Patl_3791
PFAM: acetyl-CoA hydrolase/transferase; KEGG: dar:Daro_2807 acetyl-CoA hydrolase/transferase.
   
 0.929
Your Current Organism:
Pseudoalteromonas atlantica
NCBI taxonomy Id: 342610
Other names: P. atlantica T6c, Pseudoalteromonas atlantica T6c, Pseudoalteromonas atlantica str. T6c, Pseudoalteromonas atlantica strain T6c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.