STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Patl_1978PFAM: alpha/beta hydrolase fold; KEGG: ilo:IL2157 homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (400 aa)    
Predicted Functional Partners:
Patl_3406
O-acetylhomoserine sulfhydrolase; KEGG: ppr:PBPRB1415 putative homocysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes DegT/DnrJ/EryC1/StrS aminotransferase aromatic amino acid beta-eliminating lyase/threonine aldolase.
 
 
 0.976
Patl_0616
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: ssp:SSP0251 O-acetylhomoserine sulfhydrylase.
 
  
 0.953
Patl_3580
KEGG: cps:CPS_4291 aspartokinase/homoserine dehydrogenase, threonine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 
 0.952
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
     
  0.900
Patl_1976
TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pha:PSHAa2944 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.861
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.841
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.828
Patl_1278
KEGG: cps:CPS_1107 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase-like hydrolase Haloacid dehalogenase-like hydrolase, type 3.
   
 
 0.806
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.804
Patl_1340
KEGG: ilo:IL1180 phosphatidylserine synthase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.800
Your Current Organism:
Pseudoalteromonas atlantica
NCBI taxonomy Id: 342610
Other names: P. atlantica T6c, Pseudoalteromonas atlantica T6c, Pseudoalteromonas atlantica str. T6c, Pseudoalteromonas atlantica strain T6c
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