STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Patl_3155RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: son:SO1342 RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)    
Predicted Functional Partners:
Patl_3154
Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...]
 
 
 0.964
Patl_3153
PFAM: MucB/RseB; KEGG: cps:CPS_4127 sigma-E factor regulatory protein RseB.
 
 
 0.876
recO
DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
     0.782
Patl_3152
PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: vpa:VP2575 sigma-E factor regulatory protein RseC.
  
  
 0.763
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.688
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
     
 0.685
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.681
Patl_3150
Signal peptidase I, Serine peptidase, MEROPS family S26A; KEGG: ilo:IL0811 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Belongs to the peptidase S26 family.
       0.681
Patl_1656
RNA polymerase, sigma-24 subunit, RpoE; PFAM: sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: cps:CPS_3165 RNA polymerase sigma-70 factor, ECF subfamily.
  
   
 0.624
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
       0.578
Your Current Organism:
Pseudoalteromonas atlantica
NCBI taxonomy Id: 342610
Other names: P. atlantica T6c, Pseudoalteromonas atlantica T6c, Pseudoalteromonas atlantica str. T6c, Pseudoalteromonas atlantica strain T6c
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