STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VE01_06286Replication factor C subunit 1. (1046 aa)    
Predicted Functional Partners:
VE01_08130
Rep_fac_C domain-containing protein.
   
 0.999
RFC5
Replication factor C (RF-C) subunit.
   
 0.999
VE01_03074
AAA domain-containing protein.
   
0.999
RFC4
Replication factor C subunit 4.
   
0.999
RAD30
DNA-directed DNA polymerase eta.
   
 0.996
VE01_03204
3'-5' exonuclease domain-containing protein.
   
 0.993
VE01_08157
Vezatin domain-containing protein.
   
 0.975
POL30
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.975
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.939
RAD17
Cell cycle checkpoint protein rad17.
   
 0.938
Your Current Organism:
Pseudogymnoascus verrucosus
NCBI taxonomy Id: 342668
Other names: P. verrucosus, UAMH 10579
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.