node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SG0524 | cysC | SG0524 | SG0523 | Conserved hypothetical protein. | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.666 |
SG0524 | cysD | SG0524 | SG0521 | Conserved hypothetical protein. | ATP-sulfurylase subunit 2. | 0.619 |
SG0524 | cysG | SG0524 | SG0520 | Conserved hypothetical protein. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.647 |
SG0524 | cysN | SG0524 | SG0522 | Conserved hypothetical protein. | ATP-sulfurylase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.659 |
SG0524 | ftsB | SG0524 | SG0525 | Conserved hypothetical protein. | Conserved hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.519 |
SG0524 | ispD | SG0524 | SG0526 | Conserved hypothetical protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.493 |
SG0524 | ispF | SG0524 | SG0527 | Conserved hypothetical protein. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.493 |
cysC | SG0524 | SG0523 | SG0524 | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Conserved hypothetical protein. | 0.666 |
cysC | cysD | SG0523 | SG0521 | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase subunit 2. | 0.999 |
cysC | cysG | SG0523 | SG0520 | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.988 |
cysC | cysN | SG0523 | SG0522 | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysC | ftsB | SG0523 | SG0525 | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Conserved hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.428 |
cysD | SG0524 | SG0521 | SG0524 | ATP-sulfurylase subunit 2. | Conserved hypothetical protein. | 0.619 |
cysD | cysC | SG0521 | SG0523 | ATP-sulfurylase subunit 2. | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
cysD | cysG | SG0521 | SG0520 | ATP-sulfurylase subunit 2. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.984 |
cysD | cysN | SG0521 | SG0522 | ATP-sulfurylase subunit 2. | ATP-sulfurylase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysG | SG0524 | SG0520 | SG0524 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein. | 0.647 |
cysG | cysC | SG0520 | SG0523 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Adenosine 5-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.988 |
cysG | cysD | SG0520 | SG0521 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | ATP-sulfurylase subunit 2. | 0.984 |
cysG | cysN | SG0520 | SG0522 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | ATP-sulfurylase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.883 |