node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SG1571 | dinG | SG1571 | SG0916 | Putative ATP-dependent helicase. | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | 0.987 |
SG1571 | rapA | SG1571 | SG0430 | Putative ATP-dependent helicase. | RNA polymerase associated helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.927 |
SG1571 | xni | SG1571 | SG1952 | Putative ATP-dependent helicase. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.803 |
SG2337 | dinG | SG2337 | SG0916 | ATP-dependent DNA helicase RecQ. | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | 0.594 |
SG2337 | dnaN | SG2337 | SG0002 | ATP-dependent DNA helicase RecQ. | DNA polymerase III beta subunit protein DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | 0.773 |
SG2337 | holB | SG2337 | SG1066 | ATP-dependent DNA helicase RecQ. | DNA polymerase III delta prime subunit. | 0.754 |
SG2337 | mutL | SG2337 | SG0335 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.867 |
SG2337 | mutS | SG2337 | SG0531 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.734 |
SG2337 | rapA | SG2337 | SG0430 | ATP-dependent DNA helicase RecQ. | RNA polymerase associated helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.911 |
SG2337 | recA | SG2337 | SG0537 | ATP-dependent DNA helicase RecQ. | DNA recombinase A RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.930 |
SG2337 | xni | SG2337 | SG1952 | ATP-dependent DNA helicase RecQ. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.846 |
dinG | SG1571 | SG0916 | SG1571 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | Putative ATP-dependent helicase. | 0.987 |
dinG | SG2337 | SG0916 | SG2337 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | ATP-dependent DNA helicase RecQ. | 0.594 |
dinG | dnaN | SG0916 | SG0002 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA polymerase III beta subunit protein DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | 0.830 |
dinG | holB | SG0916 | SG1066 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA polymerase III delta prime subunit. | 0.814 |
dinG | mutL | SG0916 | SG0335 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.605 |
dinG | rapA | SG0916 | SG0430 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | RNA polymerase associated helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.890 |
dinG | recA | SG0916 | SG0537 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA recombinase A RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.597 |
dinG | xni | SG0916 | SG1952 | Putative ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. | Exodeoxyribonuclease IX; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.751 |
dnaN | SG2337 | SG0002 | SG2337 | DNA polymerase III beta subunit protein DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | ATP-dependent DNA helicase RecQ. | 0.773 |