node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SG0266 | acrB_1 | SG0266 | SG0684 | Outer membrane protein TolC precursor. | Acriflavin efflux protein AcrB. | 0.988 |
SG0266 | barA | SG0266 | SG0508 | Outer membrane protein TolC precursor. | Two-component regulatory protein. | 0.430 |
SG0266 | lolD | SG0266 | SG1077 | Outer membrane protein TolC precursor. | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.458 |
SG0266 | macB | SG0266 | SG1459 | Outer membrane protein TolC precursor. | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.950 |
SG0266 | macB_1 | SG0266 | SG0533 | Outer membrane protein TolC precursor. | Putative ABC transporter ATP-binding component. | 0.458 |
SG0266 | mdtA | SG0266 | SG2093 | Outer membrane protein TolC precursor. | Putative efflux transport protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.738 |
acrB_1 | SG0266 | SG0684 | SG0266 | Acriflavin efflux protein AcrB. | Outer membrane protein TolC precursor. | 0.988 |
acrB_1 | barA | SG0684 | SG0508 | Acriflavin efflux protein AcrB. | Two-component regulatory protein. | 0.417 |
acrB_1 | macB | SG0684 | SG1459 | Acriflavin efflux protein AcrB. | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.577 |
acrB_1 | mdtA | SG0684 | SG2093 | Acriflavin efflux protein AcrB. | Putative efflux transport protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.942 |
barA | SG0266 | SG0508 | SG0266 | Two-component regulatory protein. | Outer membrane protein TolC precursor. | 0.430 |
barA | acrB_1 | SG0508 | SG0684 | Two-component regulatory protein. | Acriflavin efflux protein AcrB. | 0.417 |
barA | macB | SG0508 | SG1459 | Two-component regulatory protein. | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.501 |
barA | mdtA | SG0508 | SG2093 | Two-component regulatory protein. | Putative efflux transport protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.403 |
lolD | SG0266 | SG1077 | SG0266 | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | Outer membrane protein TolC precursor. | 0.458 |
lolD | macB | SG1077 | SG1459 | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.840 |
lolD | mdtA | SG1077 | SG2093 | Lipoprotein releasing system ATP-binding protein lolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | Putative efflux transport protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.486 |
macB | SG0266 | SG1459 | SG0266 | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Outer membrane protein TolC precursor. | 0.950 |
macB | acrB_1 | SG1459 | SG0684 | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Acriflavin efflux protein AcrB. | 0.577 |
macB | barA | SG1459 | SG0508 | Putative ABC transporter ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Two-component regulatory protein. | 0.501 |