STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvHUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)    
Predicted Functional Partners:
gcvP
Unannotated protein; Belongs to the GcvP family.
 
 0.999
gcvT
Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine.
 0.999
glyA
Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.997
lpd_2
Unannotated protein.
 
  
 0.981
LpdA-2
Unannotated protein.
 
  
 0.981
LpdA
Unannotated protein.
 
  
 0.974
lpd_1
Unannotated protein.
 
  
 0.973
folD
Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.950
metF
Unannotated protein; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.935
metH_2
Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.922
Your Current Organism:
Empedobacter falsenii
NCBI taxonomy Id: 343874
Other names: CCUG 51536, CIP 108861, E. falsenii, Empedobacter falsenii (Kampfer et al. 2006) Zhang et al. 2014, Wautersiella falsenii, Wautersiella falsenii (Kampfer et al. 2006) emend. Zhang et al. 2014, strain NF 993
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.