node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACD06420.1 | dld | SbBS512_E2391 | SbBS512_E0839 | Identified by match to protein family HMM PF00753. | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 0.907 |
ACD06420.1 | gloA | SbBS512_E2391 | SbBS512_E1843 | Identified by match to protein family HMM PF00753. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.926 |
ACD06420.1 | gloB | SbBS512_E2391 | SbBS512_E0208 | Identified by match to protein family HMM PF00753. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.915 |
ACD06420.1 | hchA | SbBS512_E2391 | SbBS512_E0916 | Identified by match to protein family HMM PF00753. | Chaperone protein HchA; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), pre [...] | 0.908 |
ACD06420.1 | idhA | SbBS512_E2391 | SbBS512_E1618 | Identified by match to protein family HMM PF00753. | D-lactate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.911 |
aldA | dld | SbBS512_E1635 | SbBS512_E0839 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | 0.901 |
aldA | ghrA | SbBS512_E1635 | SbBS512_E2296 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.909 |
aldA | gloA | SbBS512_E1635 | SbBS512_E1843 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.902 |
aldA | hchA | SbBS512_E1635 | SbBS512_E0916 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | Chaperone protein HchA; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), pre [...] | 0.905 |
aldA | idhA | SbBS512_E1635 | SbBS512_E1618 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | D-lactate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.906 |
aldA | tkrA | SbBS512_E1635 | SbBS512_E3973 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.903 |
aldA | trpA | SbBS512_E1635 | SbBS512_E1485 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.811 |
aldA | trpB | SbBS512_E1635 | SbBS512_E1486 | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.810 |
dld | ACD06420.1 | SbBS512_E0839 | SbBS512_E2391 | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Identified by match to protein family HMM PF00753. | 0.907 |
dld | aldA | SbBS512_E0839 | SbBS512_E1635 | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.901 |
dld | gloB | SbBS512_E0839 | SbBS512_E0208 | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.907 |
dld | hchA | SbBS512_E0839 | SbBS512_E0916 | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | Chaperone protein HchA; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), pre [...] | 0.901 |
dld | idhA | SbBS512_E0839 | SbBS512_E1618 | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. | D-lactate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.917 |
ghrA | aldA | SbBS512_E2296 | SbBS512_E1635 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | Aldehyde dehydrogenase A; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.909 |
ghrA | gloA | SbBS512_E2296 | SbBS512_E1843 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.901 |