STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MaeAMalate oxidoreductase; COG0281 Malic enzyme. (556 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.950
Pyk
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.946
KorA
COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
  
 
 0.936
Ldh
COG0039 Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily.
  
 0.933
CfiB
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.933
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.933
aceE
Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.922
LdhA
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.918
KorB
COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
     
 0.916
PpsA_2
COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
  
 
 0.915
Your Current Organism:
Gimesia maris
NCBI taxonomy Id: 344747
Other names: G. maris DSM 8797, Gimesia maris DSM 8797, Planctomyces maris DSM 8797, Planctomyces maris str. DSM 8797, Planctomyces maris strain DSM 8797
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