EDL60837.1 protein (Gimesia maris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

EDL60837.1

Hypothetical protein. (379 aa)

Predicted Functional Partners:

YbiA_1

0.573

YbiA_2

0.568

HpxO_2

0.567

EDL61569.1

0.556

EDL59479.1

0.547

EDL61218.1

0.522

EDL60564.1

0.520

EDL56528.1

0.517

EDL60096.1

0.462

EDL61562.1

0.455

Your Current Organism:

Gimesia maris

NCBI taxonomy Id: 344747
Other names: G. maris DSM 8797, Gimesia maris DSM 8797, Planctomyces maris DSM 8797, Planctomyces maris str. DSM 8797, Planctomyces maris strain DSM 8797

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDL56528.1	EDL59479.1	PM8797T_00909	PM8797T_03970	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	Hypothetical protein.	0.554
EDL56528.1	EDL60096.1	PM8797T_00909	PM8797T_18519	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	0.441
EDL56528.1	EDL60564.1	PM8797T_00909	PM8797T_10949	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	Uncharacterized iron-regulated protein.	0.602
EDL56528.1	EDL60837.1	PM8797T_00909	PM8797T_26755	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	Hypothetical protein.	0.517
EDL56528.1	EDL61218.1	PM8797T_00909	PM8797T_03284	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	Uncharacterized iron-regulated protein.	0.613
EDL56528.1	YbiA_1	PM8797T_00909	PM8797T_29763	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	COG3236 Uncharacterized protein conserved in bacteria.	0.546
EDL56528.1	YbiA_2	PM8797T_00909	PM8797T_20343	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	COG3236 Uncharacterized protein conserved in bacteria.	0.550
EDL59479.1	EDL56528.1	PM8797T_03970	PM8797T_00909	Hypothetical protein.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.554
EDL59479.1	EDL60096.1	PM8797T_03970	PM8797T_18519	Hypothetical protein.	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	0.437
EDL59479.1	EDL60837.1	PM8797T_03970	PM8797T_26755	Hypothetical protein.	Hypothetical protein.	0.547
EDL59479.1	EDL61562.1	PM8797T_03970	PM8797T_04655	Hypothetical protein.	COG2453 Predicted protein-tyrosine phosphatase.	0.510
EDL59479.1	EDL61569.1	PM8797T_03970	PM8797T_04690	Hypothetical protein.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.486
EDL60096.1	EDL56528.1	PM8797T_18519	PM8797T_00909	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.441
EDL60096.1	EDL59479.1	PM8797T_18519	PM8797T_03970	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	Hypothetical protein.	0.437
EDL60096.1	EDL60837.1	PM8797T_18519	PM8797T_26755	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	Hypothetical protein.	0.462
EDL60096.1	EDL61569.1	PM8797T_18519	PM8797T_04690	Hypothetical protein; COG3344 Retron-type reverse transcriptase.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.428
EDL60564.1	EDL56528.1	PM8797T_10949	PM8797T_00909	Uncharacterized iron-regulated protein.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.602
EDL60564.1	EDL60837.1	PM8797T_10949	PM8797T_26755	Uncharacterized iron-regulated protein.	Hypothetical protein.	0.520
EDL60564.1	EDL61569.1	PM8797T_10949	PM8797T_04690	Uncharacterized iron-regulated protein.	Phage tail assembly-like protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.	0.440
EDL60564.1	YbiA_1	PM8797T_10949	PM8797T_29763	Uncharacterized iron-regulated protein.	COG3236 Uncharacterized protein conserved in bacteria.	0.562

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

50

PPI enrichment p-value:

0.0574

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 107

1.37

2.49

1.44e-12

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 53

1.63

3.59

2.62e-13

GO:0019843

rRNA binding

5 of 41

1.45

1.5

0.00012

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 55

1.62

3.61

6.40e-14

GO:0005622

Intracellular anatomical structure

11 of 1004

0.4

0.34

0.00068

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:113

Structural constituent of ribosome, and Translation regulator activity

10 of 65

1.55

3.13

1.71e-12

CL:125

Structural constituent of ribosome

7 of 33

1.69

3.05

2.09e-09

CL:127

rRNA-binding

5 of 20

1.76

2.51

8.96e-07

CL:128

rRNA-binding

4 of 15

1.79

2.08

2.24e-05

CL:232

Mixed, incl. RF-1 domain, and Ribonuclease III domain

3 of 5

2.14

2.04

9.87e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 54

1.63

3.64

6.56e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

6 of 42

1.51

1.98

3.19e-06

GOCC:0043232

Intracellular non-membrane-bounded organelle

7 of 117

1.14

1.28

8.84e-06

GOCC:0043229

Intracellular organelle

9 of 228

0.96

1.02

3.19e-06

GOCC:0005622

Intracellular

11 of 992

0.4

0.34

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 54

1.63

3.62

9.42e-14

KW-0699

rRNA-binding

5 of 40

1.46

1.65

3.36e-05

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