STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (624 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.995
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.991
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.987
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.986
KRG69597.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.975
KRG69172.1
Stringent starvation protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.966
nusA
Transcription elongation factor NusA; Participates in both transcription termination and antitermination.
  
 
 0.954
KRG68471.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.911
KRG69604.1
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.904
dksA
Molecular chaperone DnaK; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
  
 
 
 0.894
Your Current Organism:
Pseudoxanthomonas dokdonensis
NCBI taxonomy Id: 344882
Other names: CIP 108839, DSM 21858, KCTC 12543, Pseudoxanthomonas dokdonensis (Yoon et al. 2006) Lee et al. 2008, Stenotrophomonas dokdonensis, Stenotrophomonas dokdonensis Yoon et al. 2006, strain DS-16
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