STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A090LDP1Helix loop helix protein 106. (1231 aa)    
Predicted Functional Partners:
A0A090KY14
Niemann-Pick C1 protein.
   
 0.986
A0A090LJ25
Importin subunit beta.
    
 0.939
A0A090LC48
Membrane-bound transcription factor site-2 protease.
    
 0.904
A0A090LKR5
Protein max.
    
 0.862
A0A090N0S9
Myc-type, basic helix-loop-helix (BHLH) domain-containing protein.
    
 0.862
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.838
A0A090L106
3-hydroxy-3-methylglutaryl coenzyme A reductase.
     
 0.818
A0A090LI18
Uncharacterized protein.
   
 
 0.783
A0A090LDR9
Histone acetyltransferase p300.
    
 0.768
A0A090LTG1
Coactivator CBP, KIX domain-containing protein.
    
 0.700
Your Current Organism:
Strongyloides ratti
NCBI taxonomy Id: 34506
Other names: S. ratti
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.