STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A090LEI9Transcription elongation factor SPT5. (763 aa)    
Predicted Functional Partners:
A0A090LCW0
RNA polymerase-associated protein LEO1.
   
 0.996
A0A090MZ01
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.966
A0A090MYQ9
FACT complex subunit SPT16.
   
 0.963
A0A090MYK2
DNA-directed RNA polymerase II subunit RPB3.
    
 0.960
A0A090L7L0
DNA-directed RNA polymerase II subunit RPB4.
    
 0.959
A0A090MXK8
DNA-directed RNA polymerase II subunit RPB7.
    
 0.959
A0A090MZQ0
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
 0.959
A0A090L8K7
DNA-directed RNA polymerases I, II, and III subunit RPABC2.
    
 0.957
A0A090LKN8
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
 0.952
A0A090LG02
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.951
Your Current Organism:
Strongyloides ratti
NCBI taxonomy Id: 34506
Other names: S. ratti
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.