EWM14181.1 protein (Kutzneria sp. 744) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EWM14181.1

Heat shock protein HtrA. (399 aa)

Predicted Functional Partners:

arc

0.881

glpK

0.815

glpK-2

0.815

glpK-3

0.815

EWM13404.1

0.802

EWM11860.1

0.738

EWM14917.1

0.669

rplY

0.660

EWM17230.1

0.654

EWM09831.1

0.653

Your Current Organism:

Kutzneria sp. 744

NCBI taxonomy Id: 345341
Other names: K. sp. 744

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EWM09831.1	EWM11860.1	KUTG_00135	KUTG_02164	LigA protein.	Serine protease PepD.	0.523
EWM09831.1	EWM13404.1	KUTG_00135	KUTG_03708	LigA protein.	Mov34/MPN/PAD-1 family protein.	0.803
EWM09831.1	EWM14181.1	KUTG_00135	KUTG_04485	LigA protein.	Heat shock protein HtrA.	0.653
EWM09831.1	EWM14917.1	KUTG_00135	KUTG_05221	LigA protein.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.870
EWM09831.1	EWM17230.1	KUTG_00135	KUTG_07534	LigA protein.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.772
EWM09831.1	rplY	KUTG_00135	KUTG_04417	LigA protein.	50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	0.797
EWM11860.1	EWM09831.1	KUTG_02164	KUTG_00135	Serine protease PepD.	LigA protein.	0.523
EWM11860.1	EWM13404.1	KUTG_02164	KUTG_03708	Serine protease PepD.	Mov34/MPN/PAD-1 family protein.	0.802
EWM11860.1	EWM14181.1	KUTG_02164	KUTG_04485	Serine protease PepD.	Heat shock protein HtrA.	0.738
EWM11860.1	EWM14917.1	KUTG_02164	KUTG_05221	Serine protease PepD.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.654
EWM11860.1	EWM17230.1	KUTG_02164	KUTG_07534	Serine protease PepD.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.693
EWM11860.1	arc	KUTG_02164	KUTG_08415	Serine protease PepD.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.881
EWM11860.1	glpK	KUTG_02164	KUTG_03830	Serine protease PepD.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.815
EWM11860.1	glpK-2	KUTG_02164	KUTG_03833	Serine protease PepD.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.815
EWM11860.1	glpK-3	KUTG_02164	KUTG_06091	Serine protease PepD.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.815
EWM11860.1	rplY	KUTG_02164	KUTG_04417	Serine protease PepD.	50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	0.649
EWM13404.1	EWM09831.1	KUTG_03708	KUTG_00135	Mov34/MPN/PAD-1 family protein.	LigA protein.	0.803
EWM13404.1	EWM11860.1	KUTG_03708	KUTG_02164	Mov34/MPN/PAD-1 family protein.	Serine protease PepD.	0.802
EWM13404.1	EWM14181.1	KUTG_03708	KUTG_04485	Mov34/MPN/PAD-1 family protein.	Heat shock protein HtrA.	0.802
EWM13404.1	arc	KUTG_03708	KUTG_08415	Mov34/MPN/PAD-1 family protein.	Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.976