STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase.
 
 0.988
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.970
AAY42_12150
Succinate dehydrogenase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.969
AAY42_09075
Malic enzyme.
  
 
 0.947
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.928
AAY42_06665
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase.
   
  0.856
AAY42_09250
Fumarylacetoacetase.
   
  0.856
argH
Argininosuccinate lyase.
   
 
 0.856
AAY42_07245
Aminotransferase.
    
  0.854
AAY42_07535
Aminotransferase.
    
  0.854
Your Current Organism:
Flagellimonas eckloniae
NCBI taxonomy Id: 346185
Other names: F. eckloniae, Flagellimonas eckloniae Bae et al. 2007, Flagellimonas sp. DK169, Flavobacteriaceae bacterium DOKDO 007, JCM 13831, KCCM 42307, strain DOKDO 007
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.