node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAY42_04770 | AAY42_13710 | AAY42_04770 | AAY42_13710 | dTTP/UTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Tryptophan 2,3-dioxygenase. | 0.522 |
AAY42_09865 | AAY42_13710 | AAY42_09865 | AAY42_13710 | Metal-dependent hydrolase. | Tryptophan 2,3-dioxygenase. | 0.971 |
AAY42_09865 | kmo | AAY42_09865 | AAY42_07310 | Metal-dependent hydrolase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.933 |
AAY42_09865 | kynU | AAY42_09865 | AAY42_07350 | Metal-dependent hydrolase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.983 |
AAY42_09865 | nbaC | AAY42_09865 | AAY42_13495 | Metal-dependent hydrolase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.510 |
AAY42_13705 | AAY42_13710 | AAY42_13705 | AAY42_13710 | ATP-dependent exonuclease. | Tryptophan 2,3-dioxygenase. | 0.867 |
AAY42_13705 | AAY42_13715 | AAY42_13705 | AAY42_13715 | ATP-dependent exonuclease. | Peptidase M23. | 0.762 |
AAY42_13705 | pgi | AAY42_13705 | AAY42_13720 | ATP-dependent exonuclease. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.819 |
AAY42_13710 | AAY42_04770 | AAY42_13710 | AAY42_04770 | Tryptophan 2,3-dioxygenase. | dTTP/UTP pyrophosphatase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.522 |
AAY42_13710 | AAY42_09865 | AAY42_13710 | AAY42_09865 | Tryptophan 2,3-dioxygenase. | Metal-dependent hydrolase. | 0.971 |
AAY42_13710 | AAY42_13705 | AAY42_13710 | AAY42_13705 | Tryptophan 2,3-dioxygenase. | ATP-dependent exonuclease. | 0.867 |
AAY42_13710 | AAY42_13715 | AAY42_13710 | AAY42_13715 | Tryptophan 2,3-dioxygenase. | Peptidase M23. | 0.762 |
AAY42_13710 | AAY42_15440 | AAY42_13710 | AAY42_15440 | Tryptophan 2,3-dioxygenase. | Phenylalanine 4-monooxygenase. | 0.498 |
AAY42_13710 | kmo | AAY42_13710 | AAY42_07310 | Tryptophan 2,3-dioxygenase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.785 |
AAY42_13710 | kynU | AAY42_13710 | AAY42_07350 | Tryptophan 2,3-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.988 |
AAY42_13710 | nbaC | AAY42_13710 | AAY42_13495 | Tryptophan 2,3-dioxygenase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.686 |
AAY42_13710 | pgi | AAY42_13710 | AAY42_13720 | Tryptophan 2,3-dioxygenase. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.818 |
AAY42_13710 | trpA | AAY42_13710 | AAY42_07090 | Tryptophan 2,3-dioxygenase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.842 |
AAY42_13715 | AAY42_13705 | AAY42_13715 | AAY42_13705 | Peptidase M23. | ATP-dependent exonuclease. | 0.762 |
AAY42_13715 | AAY42_13710 | AAY42_13715 | AAY42_13710 | Peptidase M23. | Tryptophan 2,3-dioxygenase. | 0.762 |