C5167_011656 protein (Papaver somniferum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

C5167_011656

Uncharacterized protein. (467 aa)

Predicted Functional Partners:

C5167_002470

0.766

C5167_049081

0.746

C5167_002389

0.746

C5167_047075

0.729

C5167_018735

0.660

C5167_048780

0.660

C5167_043085

0.660

C5167_031923

0.645

C5167_024254

0.640

C5167_032110

0.640

Your Current Organism:

Papaver somniferum

NCBI taxonomy Id: 3469
Other names: P. somniferum, Papaver somniferum L., Papaver somniferum convar. nigrum (Hayne) Alef., opium poppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5167_002389	C5167_002470	A0A4Y7L0G2	A0A4Y7KY71	Uncharacterized protein.	RECA_2 domain-containing protein.	0.980
C5167_002389	C5167_011656	A0A4Y7L0G2	A0A4Y7K3N0	Uncharacterized protein.	Uncharacterized protein.	0.746
C5167_002389	C5167_018735	A0A4Y7L0G2	A0A4Y7INQ2	Uncharacterized protein.	Uncharacterized protein.	0.917
C5167_002389	C5167_024254	A0A4Y7L0G2	A0A4Y7JN25	Uncharacterized protein.	RECA_2 domain-containing protein.	0.828
C5167_002389	C5167_031923	A0A4Y7L0G2	A0A4Y7K750	Uncharacterized protein.	Uncharacterized protein.	0.777
C5167_002389	C5167_032110	A0A4Y7L0G2	A0A4Y7K6K3	Uncharacterized protein.	RECA_2 domain-containing protein.	0.828
C5167_002389	C5167_043085	A0A4Y7L0G2	A0A4Y7L6D0	Uncharacterized protein.	RECA_2 domain-containing protein.	0.917
C5167_002389	C5167_047075	A0A4Y7L0G2	A0A4Y7LJD7	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.586
C5167_002389	C5167_048780	A0A4Y7L0G2	A0A4Y7KMA7	Uncharacterized protein.	RECA_2 domain-containing protein.	0.917
C5167_002470	C5167_002389	A0A4Y7KY71	A0A4Y7L0G2	RECA_2 domain-containing protein.	Uncharacterized protein.	0.980
C5167_002470	C5167_011656	A0A4Y7KY71	A0A4Y7K3N0	RECA_2 domain-containing protein.	Uncharacterized protein.	0.766
C5167_002470	C5167_018735	A0A4Y7KY71	A0A4Y7INQ2	RECA_2 domain-containing protein.	Uncharacterized protein.	0.989
C5167_002470	C5167_024254	A0A4Y7KY71	A0A4Y7JN25	RECA_2 domain-containing protein.	RECA_2 domain-containing protein.	0.920
C5167_002470	C5167_031923	A0A4Y7KY71	A0A4Y7K750	RECA_2 domain-containing protein.	Uncharacterized protein.	0.920
C5167_002470	C5167_032110	A0A4Y7KY71	A0A4Y7K6K3	RECA_2 domain-containing protein.	RECA_2 domain-containing protein.	0.920
C5167_002470	C5167_043085	A0A4Y7KY71	A0A4Y7L6D0	RECA_2 domain-containing protein.	RECA_2 domain-containing protein.	0.991
C5167_002470	C5167_047075	A0A4Y7KY71	A0A4Y7LJD7	RECA_2 domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.870
C5167_002470	C5167_048780	A0A4Y7KY71	A0A4Y7KMA7	RECA_2 domain-containing protein.	RECA_2 domain-containing protein.	0.991
C5167_002470	C5167_049081	A0A4Y7KY71	A0A4Y7KN50	RECA_2 domain-containing protein.	Uncharacterized protein.	0.980
C5167_011656	C5167_002389	A0A4Y7K3N0	A0A4Y7L0G2	Uncharacterized protein.	Uncharacterized protein.	0.746

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Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.826

expected number of edges:

12

PPI enrichment p-value:

1.85e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042274

Ribosomal small subunit biogenesis

6 of 82

2.23

4.13

2.29e-09

GO:0006412

Translation

7 of 363

1.65

2.66

4.73e-08

GO:0030490

Maturation of SSU-rRNA

4 of 67

2.14

2.6

5.68e-06

GO:0006364

rRNA processing

5 of 268

1.64

1.99

1.31e-05

GO:0000462

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

3 of 52

2.13

1.86

0.00024

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 183

1.95

3.84

5.95e-10

GO:0030515

snoRNA binding

2 of 23

2.3

0.92

0.0206

GO:0003723

RNA binding

5 of 763

1.18

0.85

0.0053

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022627

Cytosolic small ribosomal subunit

5 of 27

2.63

4.96

2.91e-10

GO:0015935

Small ribosomal subunit

6 of 59

2.37

4.94

8.00e-11

GO:0005840

Ribosome

7 of 202

1.91

3.83

2.91e-10

GO:1990904

Ribonucleoprotein complex

8 of 551

1.53

2.65

1.59e-09

GO:0030684

Preribosome

4 of 107

1.94

2.35

9.86e-06

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:10688

Cytosolic small ribosomal subunit, and Ribosomal protein S8

5 of 13

2.95

5.34

1.20e-10

CL:11902

Preribosome, small subunit precursor

3 of 5

3.14

3.45

5.25e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 217

1.87

3.81

1.81e-10

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-6791226

Major pathway of rRNA processing in the nucleolus and cytosol

8 of 182

2.01

4.81

1.23e-12

MAP-8868773

rRNA processing in the nucleus and cytosol

8 of 185

2.0

4.79

1.23e-12

MAP-72312

rRNA processing

8 of 188

1.99

4.76

1.23e-12

MAP-72695

Formation of the ternary complex, and subsequently, the 43S complex

6 of 103

2.13

4.25

4.48e-10

MAP-72702

Ribosomal scanning and start codon recognition

6 of 124

2.05

3.96

1.10e-09

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015935

Small ribosomal subunit

7 of 73

2.35

5.74

7.38e-13

GOCC:0022627

Cytosolic small ribosomal subunit

6 of 39

2.55

5.72

4.85e-12

GOCC:1990904

Ribonucleoprotein complex

9 of 532

1.59

3.18

1.42e-11

GOCC:0030684

Preribosome

3 of 83

1.92

1.62

0.00054

GOCC:0030688

Preribosome, small subunit precursor

2 of 14

2.52

1.5

0.0017

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 107

2.18

5.19

2.26e-12

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03719

Ribosomal protein S5, C-terminal domain

2 of 2

3.37

1.62

0.0012

PF00333

Ribosomal protein S5, N-terminal domain

2 of 2

3.37

1.62

0.0012

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013810

Ribosomal protein S5, N-terminal

2 of 2

3.37

1.39

0.0032

IPR005324

Ribosomal protein S5, C-terminal

2 of 2

3.37

1.39

0.0032

IPR000851

Ribosomal protein S5

2 of 2

3.37

1.39

0.0032

IPR014721

Ribosomal protein S5 domain 2-type fold, subgroup

2 of 19

2.39

0.85

0.0279

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