C5167_033980 protein (Papaver somniferum) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

C5167_033980

Uncharacterized protein; Belongs to the cytochrome P450 family. (456 aa)

Predicted Functional Partners:

C5167_015703

0.466

C5167_018333

0.463

C5167_019754

0.462

C5167_018183

0.461

C5167_021379

0.460

C5167_019753

0.458

C5167_018657

0.456

C5167_019775

0.446

C5167_041014

0.445

C5167_018371

0.445

Your Current Organism:

Papaver somniferum

NCBI taxonomy Id: 3469
Other names: P. somniferum, Papaver somniferum L., Papaver somniferum convar. nigrum (Hayne) Alef., opium poppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5167_015703	C5167_033980	A0A4Y7J6T9	A0A4Y7KFR7	Myb-like domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.466
C5167_018183	C5167_033980	A0A4Y7IQJ3	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.461
C5167_018333	C5167_033980	A0A4Y7IQ25	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.463
C5167_018371	C5167_033980	A0A4Y7IR61	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.445
C5167_018657	C5167_033980	A0A4Y7IS13	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.456
C5167_019753	C5167_033980	A0A4Y7IT58	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.458
C5167_019754	C5167_033980	A0A4Y7IUE2	A0A4Y7KFR7	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.462
C5167_019775	C5167_033980	A0A4Y7IUH2	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.446
C5167_021379	C5167_033980	A0A4Y7IZ34	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.460
C5167_033980	C5167_015703	A0A4Y7KFR7	A0A4Y7J6T9	Uncharacterized protein; Belongs to the cytochrome P450 family.	Myb-like domain-containing protein.	0.466
C5167_033980	C5167_018183	A0A4Y7KFR7	A0A4Y7IQJ3	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.461
C5167_033980	C5167_018333	A0A4Y7KFR7	A0A4Y7IQ25	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.463
C5167_033980	C5167_018371	A0A4Y7KFR7	A0A4Y7IR61	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.445
C5167_033980	C5167_018657	A0A4Y7KFR7	A0A4Y7IS13	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.456
C5167_033980	C5167_019753	A0A4Y7KFR7	A0A4Y7IT58	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.458
C5167_033980	C5167_019754	A0A4Y7KFR7	A0A4Y7IUE2	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.462
C5167_033980	C5167_019775	A0A4Y7KFR7	A0A4Y7IUH2	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.446
C5167_033980	C5167_021379	A0A4Y7KFR7	A0A4Y7IZ34	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.460
C5167_033980	C5167_041014	A0A4Y7KFR7	A0A4Y7IK03	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.445
C5167_041014	C5167_033980	A0A4Y7IK03	A0A4Y7KFR7	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.445

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

38

PPI enrichment p-value:

0.00175

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

9 of 72

1.88

4.52

2.99e-13

GO:0006352

DNA-templated transcription, initiation

7 of 61

1.84

3.57

6.70e-10

GO:0043170

Macromolecule metabolic process

10 of 1027

0.77

0.74

7.18e-06

GO:0006807

Nitrogen compound metabolic process

10 of 1666

0.56

0.47

0.00037

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

7 of 59

1.85

3.48

1.90e-09

GO:0003899

DNA-directed 5-3 RNA polymerase activity

2 of 5

2.38

1.15

0.0075

GO:0003677

DNA binding

9 of 732

0.87

0.85

2.46e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

2 of 5

2.38

1.14

0.0078

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7375

Mixed, incl. RNA polymerase sigma-70 like, and Putative zinc-finger

5 of 46

1.82

2.18

1.40e-05

CL:7376

Mixed, incl. RNA polymerase sigma-70 like, and Tetracyclin repressor-like, C-terminal, group 31

4 of 38

1.8

1.83

0.00011

CL:7379

RNA polymerase sigma-70 like, and Anti-sigma factor, zinc-finger domain superfamily

3 of 22

1.91

1.4

0.0016

CL:7385

RNA polymerase sigma-70 like

2 of 5

2.38

1.15

0.0075

CL:556

RNA polymerase

2 of 5

2.38

1.15

0.0075

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

2 of 4

2.48

1.39

0.0027

map02020

Two-component system

7 of 406

1.02

0.97

0.00013

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

9 of 106

1.71

3.74

1.80e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

7 of 46

1.96

4.12

9.57e-11

KW-0804

Transcription

9 of 336

1.21

1.69

1.36e-08

KW-0240

DNA-directed RNA polymerase

2 of 5

2.38

1.42

0.0023

KW-0238

DNA-binding

7 of 452

0.97

0.93

0.00010

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04542

Sigma-70 region 2

7 of 46

1.96

3.95

3.32e-10

PF08281

Sigma-70, region 4

5 of 21

2.16

3.36

1.05e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039425

RNA polymerase sigma-70 like

7 of 33

2.11

4.44

1.01e-10

IPR014284

RNA polymerase sigma-70 like domain

7 of 43

1.99

4.05

2.70e-10

IPR007627

RNA polymerase sigma-70 region 2

7 of 45

1.97

4.0

2.70e-10

IPR013325

RNA polymerase sigma factor, region 2

7 of 46

1.96

3.98

2.70e-10

IPR013324

RNA polymerase sigma factor, region 3/4-like

7 of 49

1.93

3.91

2.70e-10

(more ...)

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