C5167_047579 protein (Papaver somniferum) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

C5167_047579

Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (1099 aa)

Predicted Functional Partners:

C5167_013439

0.901

C5167_038112

0.886

C5167_005149

0.886

C5167_006491

0.808

C5167_000068

0.795

C5167_003197

0.795

C5167_046243

0.795

C5167_033615

0.712

C5167_001098

0.712

C5167_006176

0.647

Your Current Organism:

Papaver somniferum

NCBI taxonomy Id: 3469
Other names: P. somniferum, Papaver somniferum L., Papaver somniferum convar. nigrum (Hayne) Alef., opium poppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C5167_000068	C5167_001098	A0A4Y7KUD1	A0A4Y7KW22	B30.2/SPRY domain-containing protein.	Uncharacterized protein.	0.844
C5167_000068	C5167_005149	A0A4Y7KUD1	A0A4Y7JD54	B30.2/SPRY domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.987
C5167_000068	C5167_006176	A0A4Y7KUD1	A0A4Y7JGU8	B30.2/SPRY domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.926
C5167_000068	C5167_006491	A0A4Y7KUD1	A0A4Y7JHF4	B30.2/SPRY domain-containing protein.	Ubiquitin-like domain-containing protein.	0.908
C5167_000068	C5167_013439	A0A4Y7KUD1	A0A4Y7J4K5	B30.2/SPRY domain-containing protein.	Uncharacterized protein.	0.983
C5167_000068	C5167_033615	A0A4Y7KUD1	A0A4Y7KCC4	B30.2/SPRY domain-containing protein.	Uncharacterized protein.	0.844
C5167_000068	C5167_038112	A0A4Y7KUD1	A0A4Y7I8A4	B30.2/SPRY domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.987
C5167_000068	C5167_047579	A0A4Y7KUD1	A0A4Y7LHS2	B30.2/SPRY domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.795
C5167_001098	C5167_000068	A0A4Y7KW22	A0A4Y7KUD1	Uncharacterized protein.	B30.2/SPRY domain-containing protein.	0.844
C5167_001098	C5167_003197	A0A4Y7KW22	A0A4Y7L2Z9	Uncharacterized protein.	B30.2/SPRY domain-containing protein.	0.844
C5167_001098	C5167_005149	A0A4Y7KW22	A0A4Y7JD54	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.849
C5167_001098	C5167_006491	A0A4Y7KW22	A0A4Y7JHF4	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.965
C5167_001098	C5167_013439	A0A4Y7KW22	A0A4Y7J4K5	Uncharacterized protein.	Uncharacterized protein.	0.930
C5167_001098	C5167_033615	A0A4Y7KW22	A0A4Y7KCC4	Uncharacterized protein.	Uncharacterized protein.	0.692
C5167_001098	C5167_038112	A0A4Y7KW22	A0A4Y7I8A4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.849
C5167_001098	C5167_046243	A0A4Y7KW22	A0A4Y7LGX1	Uncharacterized protein.	B30.2/SPRY domain-containing protein.	0.844
C5167_001098	C5167_047579	A0A4Y7KW22	A0A4Y7LHS2	Uncharacterized protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.712
C5167_003197	C5167_001098	A0A4Y7L2Z9	A0A4Y7KW22	B30.2/SPRY domain-containing protein.	Uncharacterized protein.	0.844
C5167_003197	C5167_005149	A0A4Y7L2Z9	A0A4Y7JD54	B30.2/SPRY domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.987
C5167_003197	C5167_006176	A0A4Y7L2Z9	A0A4Y7JGU8	B30.2/SPRY domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.926

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

24

PPI enrichment p-value:

3.86e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042273

Ribosomal large subunit biogenesis

4 of 60

1.71

1.54

0.00045

GO:0006412

Translation

7 of 292

1.27

1.35

6.11e-05

GO:0010467

Gene expression

8 of 1030

0.78

0.61

0.0021

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

8 of 157

1.6

2.76

3.93e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022625

Cytosolic large ribosomal subunit

8 of 45

2.14

5.47

1.68e-13

GO:0032991

Protein-containing complex

10 of 1740

0.65

0.56

0.00012

GO:0043229

Intracellular organelle

11 of 4370

0.29

0.23

0.0476

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4352

GTP hydrolysis and joining of the 60S ribosomal subunit, and Translation elongation factor activity

11 of 113

1.88

5.49

6.45e-18

CL:4387

Cytosolic large ribosomal subunit

7 of 31

2.24

5.45

1.12e-12

CL:4386

Cytosolic ribosome

8 of 61

2.01

4.93

4.63e-13

CL:4389

Cytosolic large ribosomal subunit

2 of 12

2.11

1.0

0.0134

CL:4419

Cytosolic large ribosomal subunit

2 of 15

2.01

0.91

0.0189

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

8 of 175

1.55

2.75

8.97e-10

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

8 of 105

1.77

3.58

1.09e-10

MAP-72689

Formation of a pool of free 40S subunits

8 of 113

1.74

3.49

1.09e-10

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

8 of 115

1.73

3.46

1.09e-10

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

8 of 116

1.73

3.45

1.09e-10

MAP-975957

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

8 of 125

1.7

3.35

1.09e-10

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0022625

Cytosolic large ribosomal subunit

5 of 41

1.98

2.7

1.57e-06

GOCC:0005854

Nascent polypeptide-associated complex

3 of 4

2.76

2.7

1.07e-05

GOCC:0005840

Ribosome

6 of 144

1.51

1.91

5.48e-06

GOCC:1990904

Ribonucleoprotein complex

6 of 425

1.04

0.9

0.00081

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

3 of 55

1.63

0.94

0.0113

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038187

NAC A/B domain superfamily

2 of 2

2.89

0.89

0.0253

IPR002715

Nascent polypeptide-associated complex NAC domain

2 of 2

2.89

0.89

0.0253

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01407

NAC

2 of 2

2.89

1.39

0.0030

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