STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182UJB8Lipoyl-binding domain-containing protein. (493 aa)    
Predicted Functional Partners:
A0A182TH53
Transket_pyr domain-containing protein.
 
 0.999
A0A182U9P2
Dihydrolipoyl dehydrogenase.
 
 0.999
A0A182TTI2
Transket_pyr domain-containing protein.
 
 0.998
A0A1I8JV33
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.993
A0A182UHU6
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 0.990
A0A182TYX4
Citrate synthase; Belongs to the citrate synthase family.
  
 0.987
A0A182U880
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.987
A0A182ULM6
ATP-grasp domain-containing protein.
  
 0.987
A0A182TNG9
Lipoyl-binding domain-containing protein.
  
0.986
A0A182TMH6
Transket_pyr domain-containing protein.
  
 0.983
Your Current Organism:
Anopheles melas
NCBI taxonomy Id: 34690
Other names: A. melas
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.