node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALC56_00156 | ALC56_02443 | A0A195FXB8 | A0A151K0M7 | Malic enzyme. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.909 |
ALC56_00156 | ALC56_02519 | A0A195FXB8 | A0A151K0C5 | Malic enzyme. | 2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. | 0.931 |
ALC56_00156 | ALC56_03229 | A0A195FXB8 | A0A195FNV1 | Malic enzyme. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.950 |
ALC56_00156 | ALC56_03897 | A0A195FXB8 | A0A151JZ74 | Malic enzyme. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.959 |
ALC56_00156 | ALC56_06224 | A0A195FXB8 | A0A151JXL3 | Malic enzyme. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.905 |
ALC56_00156 | ALC56_07861 | A0A195FXB8 | A0A195FBS5 | Malic enzyme. | Citrate synthase; Belongs to the citrate synthase family. | 0.913 |
ALC56_00156 | ALC56_10002 | A0A195FXB8 | A0A151JUE3 | Malic enzyme. | Putative citrate synthase 1, mitochondrial. | 0.912 |
ALC56_00156 | ALC56_11142 | A0A195FXB8 | A0A195F2G6 | Malic enzyme. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.914 |
ALC56_00156 | ALC56_11545 | A0A195FXB8 | A0A195F0D8 | Malic enzyme. | Fumarate hydratase, mitochondrial. | 0.956 |
ALC56_00156 | ALC56_12246 | A0A195FXB8 | A0A195F087 | Malic enzyme. | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial. | 0.923 |
ALC56_02443 | ALC56_00156 | A0A151K0M7 | A0A195FXB8 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Malic enzyme. | 0.909 |
ALC56_02443 | ALC56_02519 | A0A151K0M7 | A0A151K0C5 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. | 0.647 |
ALC56_02443 | ALC56_03229 | A0A151K0M7 | A0A195FNV1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.933 |
ALC56_02443 | ALC56_03897 | A0A151K0M7 | A0A151JZ74 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.674 |
ALC56_02443 | ALC56_06224 | A0A151K0M7 | A0A151JXL3 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.825 |
ALC56_02443 | ALC56_07861 | A0A151K0M7 | A0A195FBS5 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Citrate synthase; Belongs to the citrate synthase family. | 0.960 |
ALC56_02443 | ALC56_10002 | A0A151K0M7 | A0A151JUE3 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Putative citrate synthase 1, mitochondrial. | 0.960 |
ALC56_02443 | ALC56_11142 | A0A151K0M7 | A0A195F2G6 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.754 |
ALC56_02443 | ALC56_11545 | A0A151K0M7 | A0A195F0D8 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Fumarate hydratase, mitochondrial. | 0.988 |
ALC56_02443 | ALC56_12246 | A0A151K0M7 | A0A195F087 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial. | 0.953 |