obg protein (Mycoplasma hominis) - STRING interaction network

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obg

GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (424 aa)

Predicted Functional Partners:

rplT

0.901

rpml

0.878

rpmA

0.878

rplU

0.866

metG

0.854

rplk

0.836

rplB

0.832

rplA

0.831

rplQ

0.831

rpmF

0.827

Your Current Organism:

Mycoplasma hominis

NCBI taxonomy Id: 347256
Other names: M. hominis ATCC 23114, Mycoplasma hominis ATCC 23114, Mycoplasma hominis PG21, Mycoplasma hominis str. ATCC 23114, Mycoplasma hominis strain ATCC 23114

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
metG	obg	MHO_1370	MHO_1380	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	0.854
metG	rplA	MHO_1370	MHO_0880	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.593
metG	rplB	MHO_1370	MHO_2950	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.644
metG	rplQ	MHO_1370	MHO_2720	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L17.	0.637
metG	rplT	MHO_1370	MHO_1290	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.670
metG	rplk	MHO_1370	MHO_0870	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.508
metG	rpmA	MHO_1370	MHO_2650	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.579
metG	rpmF	MHO_1370	MHO_2710	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.575
metG	rpml	MHO_1370	MHO_1280	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.437
obg	metG	MHO_1380	MHO_1370	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	0.854
obg	rplA	MHO_1380	MHO_0880	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.831
obg	rplB	MHO_1380	MHO_2950	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.832
obg	rplQ	MHO_1380	MHO_2720	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L17.	0.831
obg	rplT	MHO_1380	MHO_1290	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.901
obg	rplU	MHO_1380	MHO_2660	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.866
obg	rplk	MHO_1380	MHO_0870	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.836
obg	rpmA	MHO_1380	MHO_2650	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.878
obg	rpmF	MHO_1380	MHO_2710	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.827
obg	rpml	MHO_1380	MHO_1280	GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.878
rplA	metG	MHO_0880	MHO_1370	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).	0.593

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