Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
licAProtein licA homolog; Belongs to the peptidase S49 family. (249 aa)    
Predicted Functional Partners:
MHO_3780
Conserved hypothetical protein.
 
 
  
0.863
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.774
MHO_3160
Conserved hypothetical protein.
 
     0.765
MHO_0470
Conserved hypothetical protein, putativecarbohydrate kinase.
  
     0.758
MHO_3790
Hypothetical protein.
       0.757
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
 
     0.748
MHO_3140
Conserved hypothetical protein.
  
     0.744
MHO_3200
Conserved hypothetical protein, predictedlipoprotein.
  
     0.738
MHO_4480
Conserved hypothetical protein.
 
     0.733
oppA
Oligopeptide ABC transporter substrate-binding protein.
  
     0.732
Your Current Organism:
Mycoplasma hominis
NCBI taxonomy Id: 347256
Other names: M. hominis ATCC 23114, Mycoplasma hominis ATCC 23114, Mycoplasma hominis PG21, Mycoplasma hominis str. ATCC 23114, Mycoplasma hominis strain ATCC 23114
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