Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine-guanine phosphoribosyltransferase(HGPRT); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.934
rpe
Ribulose-phosphate 3-epimerase.
  
 
 0.848
MHO_4870
Protein phosphatase.
  
   0.836
engC
Probable GTPase engC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.830
sps1
Serine/threonine protein kinase.
       0.818
adk
Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.779
MHO_4910
Hypothetical protein, predicted lipoprotein.
       0.768
apt
Adenine phosphoribosyl transferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.731
arcC
Carbamate kinase; Belongs to the carbamate kinase family.
      
 0.708
dgk
Deoxyguanosine kinase.
    
 0.688
Your Current Organism:
Mycoplasma hominis
NCBI taxonomy Id: 347256
Other names: M. hominis ATCC 23114, Mycoplasma hominis ATCC 23114, Mycoplasma hominis PG21, Mycoplasma hominis str. ATCC 23114, Mycoplasma hominis strain ATCC 23114
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