| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MAG0435 | MAG0590 | MAG0435 | MAG0590 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Conserved hypothetical protein. | 0.900 |
| MAG0435 | ffh | MAG0435 | MAG5820 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Signal Recognition Particle Protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.900 |
| MAG0435 | ftsY | MAG0435 | MAG2040 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.900 |
| MAG0435 | secA | MAG0435 | MAG2730 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.900 |
| MAG0435 | secD | MAG0435 | MAG2250 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Protein export membrane protein. | 0.900 |
| MAG0435 | secY | MAG0435 | MAG5260 | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.900 |
| MAG0590 | MAG0435 | MAG0590 | MAG0435 | Conserved hypothetical protein. | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | 0.900 |
| MAG0590 | atpB | MAG0590 | MAG3500 | Conserved hypothetical protein. | ATP synthase A chain. | 0.895 |
| MAG0590 | ffh | MAG0590 | MAG5820 | Conserved hypothetical protein. | Signal Recognition Particle Protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.956 |
| MAG0590 | ftsY | MAG0590 | MAG2040 | Conserved hypothetical protein. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.941 |
| MAG0590 | rnpA | MAG0590 | MAG0580 | Conserved hypothetical protein. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.973 |
| MAG0590 | rplB | MAG0590 | MAG5430 | Conserved hypothetical protein. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.872 |
| MAG0590 | rpmH | MAG0590 | MAG7500 | Conserved hypothetical protein. | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. | 0.909 |
| MAG0590 | secA | MAG0590 | MAG2730 | Conserved hypothetical protein. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.945 |
| MAG0590 | secD | MAG0590 | MAG2250 | Conserved hypothetical protein. | Protein export membrane protein. | 0.998 |
| MAG0590 | secY | MAG0590 | MAG5260 | Conserved hypothetical protein. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.989 |
| atpB | MAG0590 | MAG3500 | MAG0590 | ATP synthase A chain. | Conserved hypothetical protein. | 0.895 |
| atpB | rplB | MAG3500 | MAG5430 | ATP synthase A chain. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.868 |
| atpB | secY | MAG3500 | MAG5260 | ATP synthase A chain. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.707 |
| ffh | MAG0435 | MAG5820 | MAG0435 | Signal Recognition Particle Protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Hypothetical protein; Belongs to the SecE/SEC61-gamma family. | 0.900 |