| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MAG0770 | glyA | MAG0770 | MAG0700 | Hypothetical protein, predicted lipoprotein. | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.648 |
| MAG0770 | mucB | MAG0770 | MAG0740 | Hypothetical protein, predicted lipoprotein. | DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | 0.752 |
| MAG0770 | nadD | MAG0770 | MAG0750 | Hypothetical protein, predicted lipoprotein. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.794 |
| MAG0770 | nifU | MAG0770 | MAG0730 | Hypothetical protein, predicted lipoprotein. | Nitrogen fixation protein NifU. | 0.752 |
| MAG0770 | pheS | MAG0770 | MAG0670 | Hypothetical protein, predicted lipoprotein. | Phenylalanyl tRNA Synthetase alpha chain (PheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.644 |
| MAG0770 | pheT | MAG0770 | MAG0690 | Hypothetical protein, predicted lipoprotein. | Phenylalanyl tRNA synthetase beta chain (PheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.644 |
| MAG0770 | rluB | MAG0770 | MAG0760 | Hypothetical protein, predicted lipoprotein. | Ribosomal large subunit pseudouridine synthaseB; Belongs to the pseudouridine synthase RsuA family. | 0.785 |
| MAG5850 | MAG5910 | MAG5850 | MAG5910 | Conserved hypothetical protein; Belongs to the NAPRTase family. | 5'Nucleotidase; Belongs to the 5'-nucleotidase family. | 0.924 |
| MAG5850 | nadD | MAG5850 | MAG0750 | Conserved hypothetical protein; Belongs to the NAPRTase family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.980 |
| MAG5850 | nadE | MAG5850 | MAG6600 | Conserved hypothetical protein; Belongs to the NAPRTase family. | NH(3) dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.492 |
| MAG5910 | MAG5850 | MAG5910 | MAG5850 | 5'Nucleotidase; Belongs to the 5'-nucleotidase family. | Conserved hypothetical protein; Belongs to the NAPRTase family. | 0.924 |
| MAG5910 | nadD | MAG5910 | MAG0750 | 5'Nucleotidase; Belongs to the 5'-nucleotidase family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.916 |
| glyA | MAG0770 | MAG0700 | MAG0770 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein, predicted lipoprotein. | 0.648 |
| glyA | mucB | MAG0700 | MAG0740 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | 0.695 |
| glyA | nadD | MAG0700 | MAG0750 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.857 |
| glyA | nifU | MAG0700 | MAG0730 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Nitrogen fixation protein NifU. | 0.689 |
| glyA | pheS | MAG0700 | MAG0670 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phenylalanyl tRNA Synthetase alpha chain (PheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.866 |
| glyA | pheT | MAG0700 | MAG0690 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phenylalanyl tRNA synthetase beta chain (PheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.887 |
| glyA | rluB | MAG0700 | MAG0760 | Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Ribosomal large subunit pseudouridine synthaseB; Belongs to the pseudouridine synthase RsuA family. | 0.658 |
| mucB | MAG0770 | MAG0740 | MAG0770 | DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | Hypothetical protein, predicted lipoprotein. | 0.752 |