nadD protein (Mycoplasma agalactiae PG2) - STRING interaction network

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nadD

Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (364 aa)

Predicted Functional Partners:

MAG5850

0.962

nadE

0.962

glyA

0.829

mucB

0.828

rluB

0.825

nifU

0.824

MAG0770

0.794

nifS

0.786

pheS

0.784

pheT

0.760

Your Current Organism:

Mycoplasma agalactiae PG2

NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAG0770	glyA	MAG0770	MAG0700	Hypothetical protein, predicted lipoprotein.	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.648
MAG0770	mucB	MAG0770	MAG0740	Hypothetical protein, predicted lipoprotein.	DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family.	0.749
MAG0770	nadD	MAG0770	MAG0750	Hypothetical protein, predicted lipoprotein.	Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.794
MAG0770	nifS	MAG0770	MAG0720	Hypothetical protein, predicted lipoprotein.	Nitrogen fixation protein NifS.	0.675
MAG0770	nifU	MAG0770	MAG0730	Hypothetical protein, predicted lipoprotein.	Nitrogen fixation protein NifU.	0.749
MAG0770	pheS	MAG0770	MAG0670	Hypothetical protein, predicted lipoprotein.	Phenylalanyl tRNA Synthetase alpha chain (PheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.	0.644
MAG0770	pheT	MAG0770	MAG0690	Hypothetical protein, predicted lipoprotein.	Phenylalanyl tRNA synthetase beta chain (PheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.644
MAG0770	rluB	MAG0770	MAG0760	Hypothetical protein, predicted lipoprotein.	Ribosomal large subunit pseudouridine synthaseB; Belongs to the pseudouridine synthase RsuA family.	0.783
MAG5850	nadD	MAG5850	MAG0750	Conserved hypothetical protein; Belongs to the NAPRTase family.	Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.962
MAG5850	nadE	MAG5850	MAG6600	Conserved hypothetical protein; Belongs to the NAPRTase family.	NH(3) dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.	0.482
glyA	MAG0770	MAG0700	MAG0770	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Hypothetical protein, predicted lipoprotein.	0.648
glyA	mucB	MAG0700	MAG0740	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family.	0.700
glyA	nadD	MAG0700	MAG0750	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.829
glyA	nifS	MAG0700	MAG0720	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Nitrogen fixation protein NifS.	0.781
glyA	nifU	MAG0700	MAG0730	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Nitrogen fixation protein NifU.	0.689
glyA	pheS	MAG0700	MAG0670	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phenylalanyl tRNA Synthetase alpha chain (PheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.	0.853
glyA	pheT	MAG0700	MAG0690	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phenylalanyl tRNA synthetase beta chain (PheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.850
glyA	rluB	MAG0700	MAG0760	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Ribosomal large subunit pseudouridine synthaseB; Belongs to the pseudouridine synthase RsuA family.	0.657
mucB	MAG0770	MAG0740	MAG0770	DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family.	Hypothetical protein, predicted lipoprotein.	0.749
mucB	glyA	MAG0740	MAG0700	DNA damage repair protein MucB; Belongs to the DNA polymerase type-Y family.	Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.700

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